dijous, 15 de gener del 2015

Mapping mosaicism: Tracing subtle mutations in our brains




Vector is Children's Hospital Boston's blog about research and innovation in pediatric and adult medicine. We report and comment on medical innovations and advances – from bench to bedside – touching on scientific, business and policy issues. Our ranks include science writers, physicians, lab researchers, market analysts and others inside and outside the hospital.








(Erik Jacobsen, Threestory Studio. Used with permission.)


By Nancy Fliesler


DNA sequences were once thought to be the same in every cell, but the story is now known to be more complicated than that. The brain is a case in point: Mutations can arise at different times in brain development and affect only a percentage of neurons, forming a mosaic pattern.




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