Researchers from Australia and the UK have developed virus-like nanoparticles to target and deliver drugs to cancer cells. The team’s work, which was published in the journal ACS Nano, showed that the particle could be produced in plants and that it can shuttle small molecules to cancer cells for targeted treatment.
The team, lead by Frank Sainsbury, modeled the core protein shell, or capsid, of the Bluetongue virus. Previous work has demonstrated that the Bluetongue virus’ shell is stable, easy to produce and has a cavity big enough for small molecules or proteins to fit into.
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