Robert Langer, a pioneer in drug delivery and the most cited engineer in history, has co-founded 30 companies and treated more than 20 million patients as a result of his innovations. In a conversation with Wired, he spoke about his career, which has spanned for 4 decades and began with his 1976 discovery of a method to delay delivery of large molecules.
Many new drugs are large molecules, Langer said, because they are complex and contain a lot of information. The structure of these large molelecules, including peptides, proteins and anitbodies, fall apart rapidly in the body. Langer knew that polymers could delay a drug’s release over a long period of time, so his team carved channels into the polymer to make the technique work for molecules of any size or charge.
Get the full story at our sister site, Drug Delivery Business News.
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