Study: Localized delivery of chemo improves prognosis of recurrent glioblastoma

Researchers from Amrita University in India demonstrated that localized and sustained delivery of a chemotherapeutic agent in brain tumors can improve the prognosis of recurrent glioblastoma. The team’s work was published in Scientific Reports.

Although new drugs have been developed for glioblastoma multiforme, the overall survival rate for patients remains dismally low at 12 months, with a 3-year long term survival rate of 3% to 5%. Newly developed drugs face several delivery-related challenges, including poor drug accumulation in the brain tumor site and the inability to sustain adequate drug concentration in the tumor.

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