Ibuprofen delivered via metal-organic framework sports doubled half-life

Researchers at Northwestern University have published data showing that metal-organic frameworks can be used to extend the duration of ibuprofen. The in vivo mouse study was published in Molecular Pharmaceutics.

Metal-organic frameworks are made up of metal ions linked to organic ligands. Since MOFs are porous, researchers pack active ingredients inside of them and use them as vessels for oral drug delivery.

“Although MOFs have been frequently discussed as potential drug-delivery vehicles, very few instances of in vivo studies involving MOFs have been reported to date,” the team said, according to New Atlas.

Get the full story at our sister site, Drug Delivery Business News.

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