Plant-virus nanoparticles combined with chemo delays tumor progression

Researchers from Case Western Reserve University School of Medicine, Dartmouth Geisel School of Medicine and RWTH Aachen University have demonstrated that injecting nanoscale potato-virus particles and doxorubicin into melanoma tumors slows tumor progression in mice. The team’s work was published in Nano Letters.

Although simultaneous injection of the virus particles and a chemo drug prompted a positive response, fusing the two into a combination nanoparticle did not add any benefit, the team reported.

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