Researchers have programmed an MRI scanner to simultaneously monitor magnetized particles while propelling them through blood vessels as a means to locally deliver drugs.
Existing approaches combine the magnetic force from an MRI scanner with the force produced by particle collisions. But traditionally, it’s challenging to image using the MRI scanner and propel the particles forcefully enough to overcome blood flow.
“Steering particles in the bloodstream is akin to whitewater rafting: You have limited paddling ability compared to the strength of the river, so you need to position yourself appropriately in the flow to follow your desired path,” Boston Children’s Hospital bioengineer lab head Pierre Dupont said, according to the hospital. “In the existing approach, the MR scanner had to be programmed to alternate between imaging the particle and propelling it. This is really inefficient since whenever you are imaging, you are not propelling and vice versa. It’s like pushing a car up the hill and continuously stopping and starting. Half the time no one is doing anything.”
Get the full story at our sister site, Drug Delivery Business News.
The post Hospital researchers explore MRI for drug delivery appeared first on MassDevice.
from MassDevice http://ift.tt/2dVxAXv
Cap comentari:
Publica un comentari a l'entrada